YAMANAKA,Kazuya - Faculty of Chemistry, Materials and Bioengineering Department of Life Science and Biotechnology

Faculty, Department/Institute

Faculty of Chemistry, Materials and Bioengineering Department of Life Science and Biotechnology

Academic status (qualification)

Professor Apr. 1,2023

Undergraduate Degrees・University

Kansai University Faculty of Engineering1999 Graduated

Graduate Degrees・University

Kansai University Master's Degree Program 2001 Completed

Academic Degrees

Ph.D Mar. 2011 Fukui Prefectural University

Homepage Address, E-mail Address

Homepage Address：http://biomole.life-bio.kansai-u.ac.jp

Research fields

Research fields	keyword
Applied microbiology	enzyme;protein
Fermentative production in general	secondary metabolism;biosynthesis;genetic engineering

Research Career

2010/7～2013年/6
2013/7～2015年/3

Awards

Oct. 2,2008

Academic Associations

所属学会・団体名	役職名 (役職在任期間)
	handling editor(2019/6/1)

Intellectual Property Rights

(Acquired)
application number：特願2008-022841
application number：特開2009-178152
application number：特許5367272
(Published)
application number：PCT/2011JP054763 (Mar. 2,2011)
application number：PCT/WO11108585 (Jun. 27,2013)
(Pending)
application number：特願2018-228001 (Dec. 5,2018)

Research Publications

No.	Type of publication	Date of publication (Date of presentation)	Title	Type of research result	Jointly authored or single authored	Publisher and journal name
1	Papers1	2020/6～2020,06,00,,,	The Stereocontrolled Biosynthesis of Mirror-Symmetric 2,4-Diaminobutyric Acid Homopolymers Is Critically Governed by Adenylation Activations.	Academic Journal	Co-authored	ACS chemical biology
2	Papers1	2020/5～2020,05,00,,,	Enhancement of metabolic flux toward ε-poly-l-lysine biosynthesis by targeted inactivation of concomitant polyene macrolide biosynthesis in Streptomyces albulus	Academic Journal	Co-authored	J Biosci Bioeng.
3	Lecture19	2019/9/18～2019,09,18,,,	TAR cloning that allows the efficient production of natural product molecules from uncharacterized gene collections	Other	Co-author
4	Academic presentation7	2019/9/18～2019,09,18,,,	Structure and bioactivity of a novel cationic homo poly-amino acid produced by Streptoalloteichus hindustanus	Other	Co-author
5	Academic presentation7	2019/9/18～2019,09,18,,,	Characterization of an unprecedented PLP-independent diaminobutyric acid racemase from Streptoalloteichus hindustanus	Other	Co-author
6	Academic presentation7	2019/3/24～2019,03,24,,,	Functional analysis of an unusual non-ribosomal peptide biosynthetic gene cluster actively expressed in Streptomyces albulus	Other	Co-author
7	Academic presentation7	2019/3/24～2019,03,24,,,	Specificity prediction of adenylation domains in ε-poly-L-lysine synthetase (Pls) homologs for exploration of novel bioactive poly-amino acids	Other	Co-author
8	Papers1	2019/1～2019,01,00,,,	Draft Genome Sequence of the Most Traditional ε-Poly-L-Lysine Producer, Streptomyces albulus NBRC14147	Academic Journal	Co-authored	Microbiol Resour Announc.
9	Academic presentation7	2018/9/11～2018/9/122018,09,11,2018,09,12	Cloning of the gene coding for novel PLP-independent diaminobutyric acid racemase involved in Poly-D-diaminobutyric acid biosynthesis	Other	Co-author
10	Academic presentation7	2018/9/11～2018/9/122018,09,11,2018,09,12	Exploration of D-peptide degrading enzyme from a poly-D-diaminobutyric acid producer, Streptoalloteichus hindustanus	Other	Co-author
11	Lecture19	2018/3/18～2018,03,18,,,	Membrane-bound NRPS-like peptide synthetases producing linear homo poly-amino acids	Other	Co-author
12	Academic presentation7	2018/3/17～2018,03,17,,,	Biosynthetic study of a novel homo poly-amino acid discovered through genome-ming.	Other	Co-author
13	Academic presentation7	2017/9/7～2017/9/82017,09,07,2017,09,08	Discovery of a homo poly-amino acid consisting of non-proteinogenic 2,4-diaminobutyric acid D-enentiomer by genome mining	Other	Co-author
14	Academic presentation7	2017/9/7～2017/9/82017,09,07,2017,09,08	Functional analysis of the condensation domains in ε-poly-L-lysine synthetase	Other	Co-author
15	Academic presentation7	2017/3/18～2017,03,18,,,	Functional analysis of the condensation domains in poly-L-lysine synthetase	Other	Co-author
16	Academic presentation7	2017/3/18～2017,03,18,,,	Improved gene cluster direct cloning system that facilitates biosynthetic study of natural products	Other	Co-author

PapersIn refereedAcademic JournalCo-author2023/6/12～https://doi.org/10.1038/s41429-023-00636-9

PapersIn refereedAcademic JournalCo-author2022/10/26～10.1038/s42003-022-04110-4

Academic presentationOtherCo-authorY2022/9/1～

Academic presentationOtherCo-author2022/9/1～

Academic presentationOtherCo-authored2022/3/17～

PapersIn refereedAcademic JournalCo-authoredOKAMOTO, Takaki;YAMANAKA, Kazuya;HAMANO, Yoshimitsu;NAGANO, Shingo;HINO, Tomoya2022/3/12～doi.org/10.1016/j.bbrc.2022.01.053

PapersIn refereedAcademic JournalCo-authoredOIKAWA, Tadao;OKAJIMA, Kouhei;YAMANAKA, Kazuya;KATO, Shiro2022/2/5～doi.org/10.1007/s00726-022-03133-9

PapersIn refereedAcademic JournalCo-authoredYAMANAKA, Kazuya;FUKUMOTO, Hibiki;YOSHIMURA, Naoki;ARAKAWA, Kenji;KATO, Yasuo;HAMANO, Yoshimitsu;OIKAWA, Tadao2021/12/10～DOI: 10.1021/acschembio.1c00832

Academic presentationUnrefereedOtherCo-authored;;YAMANAKA,Kazuya2021/10/27～2021/10/29

Academic presentationUnrefereedOtherCo-authored;;;;YAMANAKA,Kazuya2021/9/18～2021/9/19

Academic presentationUnrefereedOther;;YAMANAKA,Kazuya2021/9/18～2021/9/19

Academic presentationUnrefereedOtherCo-authored;;YAMANAKA,Kazuya2021/9/18～2021/9/19

International academic conferenceUnrefereedOtherCo-authored2021/8/5～2021/8/6

PapersIn refereedAcademic JournalCo-authoredYAMANAKA,Kazuya;OZAKI, Ryo;HAMANO, Yoshimitsu;OIKAWA, Tadao2021/6/10～10.3389/fmicb.2021.686023

PapersIn refereedAcademic JournalCo-authoredTAKEHARA, Munenori;SAIMURA, Masayuki;INABA, Haruka;KATO, Yoshinao;MURO, Shogo;MATSUNAGA, Tatsuki;YAMANAKA, Kazuya2021/4/12～10.1007/s00253-021-11257-3

PapersThe Stereocontrolled Biosynthesis of Mirror-Symmetric 2,4-Diaminobutyric Acid Homopolymers Is Critically Governed by Adenylation Activations.In refereedAcademic JournalCo-authoredYAMANAKA, Kazuya;FUKUMOTO, Hibiki;TAKEHARA, Munenori;HAMANO, Yoshimitsu;OIKAWA, TadaoACS chemical biology2020/6～ACS chemical biology10.1021/acschembio.0c00321

PapersEnhancement of metabolic flux toward ε-poly-l-lysine biosynthesis by targeted inactivation of concomitant polyene macrolide biosynthesis in Streptomyces albulusIn refereedAcademic JournalCo-authoredYAMANAKA, Kazuya;HAMANO, YoshimitsuJ Biosci Bioeng.2020/5～10.1016/j.jbiosc.2019.12.002

Academic presentationUnrefereedOtherCo-authored;YAMANAKA,Kazuya2020/3/26～2020/3/28

Academic presentationUnrefereedOtherCo-authoredYAMANAKA,Kazuya2020/3/26～2020/3/28

LectureTAR cloning that allows the efficient production of natural product molecules from uncharacterized gene collectionsOtherCo-authorYAMANAKA, Kazuya;OIKAWA, Tadao;HAMANO, Yoshimitsu2019/9/18～

Academic presentationStructure and bioactivity of a novel cationic homo poly-amino acid produced by Streptoalloteichus hindustanusOtherCo-authorFUKUMOTO, Hibiki;TOGUCHI, Rina;ARAKAWA, Kenji;HAMANO, Yoshimitsu;OIKAWA, Tadao;YAMANAKA, Kazuya2019/9/18～

Academic presentationCharacterization of an unprecedented PLP-independent diaminobutyric acid racemase from Streptoalloteichus hindustanusOtherCo-authorOZAKI, Ryo;FUKUMOTO, Hibiki;HAMANO, Yoshimitsu;OIKAWA, Tadao;YAMANAKA, Kazuya2019/9/18～

Academic presentationOtherCo-authorMIYAWAKI, Hiroki;FUKUMOTO, Hibiki;HAMANO, Yoshimitsu;;YAMANAKA, Kazuya2019/9/18～

Academic presentationFunctional analysis of an unusual non-ribosomal peptide biosynthetic gene cluster actively expressed in Streptomyces albulusUnrefereedOtherCo-authorReina Tomosugi;Ayaka Fujita;Takashi Miyamoto;Yoshimitsu Hamano;Tadao Oikawa;Kazuya Yamanaka2019/3/24～

Academic presentationSpecificity prediction of adenylation domains in ε-poly-L-lysine synthetase (Pls) homologs for exploration of novel bioactive poly-amino acidsUnrefereedOtherCo-authorHonoka Kimura;Hibiki Fukumoto;Yoshimitsu Hamano;Tadao Oikawa;Kazuya Yamanaka2019/3/24～

Academic presentationUnrefereedOtherCo-authorKazuya Tamura;Kazuya Yamanaka;Tadao Oikawa2019/3/24～

PapersIn refereedAcademic JournalInternational coauthorshipJia Jia Zhang;Kazuya Yamanaka;Xiaoyu Tang;Bradley S. Moore2019/3/21～10.1016/bs.mie.2019.02.026

PapersDraft Genome Sequence of the Most Traditional ε-Poly-L-Lysine Producer, Streptomyces albulus NBRC14147In refereedAcademic JournalCo-authoredYAMANAKA, Kazuya;HAMANO, YoshimitsuMicrobiol Resour Announc.2019/1～10.1128/MRA.01515-18.

Academic presentationOtherCo-author;;YAMANAKA,Kazuya2018/11/10～2018/11/11

Academic presentationCloning of the gene coding for novel PLP-independent diaminobutyric acid racemase involved in Poly-D-diaminobutyric acid biosynthesisOtherCo-authorOZAKI Ryo;FUKUMOTO Hibiki;HAMANO Yoshimitsu;OIKAWA Tadao;YAMANAKA,Kazuya2018/9/11～2018/9/12

Academic presentationExploration of D-peptide degrading enzyme from a poly-D-diaminobutyric acid producer, Streptoalloteichus hindustanusOtherCo-authorMIYAWAKI Hiroki;FUKUMOTO Hibiki;HAMANO Yoshimitsu;OIKAWA Tadao;YAMANAKA,Kazuya2018/9/11～2018/9/12

LectureMembrane-bound NRPS-like peptide synthetases producing linear homo poly-amino acidsOtherCo-authorYAMANAKA,Kazuya2018/3/18～

Academic presentationBiosynthetic study of a novel homo poly-amino acid discovered through genome-ming.OtherCo-author2018/3/17～

PapersIn refereedAcademic JournalInternational coauthorship2017/11/29～10.1038/ja.2017.146.

Academic presentationDiscovery of a homo poly-amino acid consisting of non-proteinogenic 2,4-diaminobutyric acid D-enentiomer by genome miningOtherCo-authorFUKUMOTO, Hibiki;OIKAWA, Tadao;YAMANAKA,Kazuya2017/9/7～2017/9/8

Academic presentationFunctional analysis of the condensation domains in ε-poly-L-lysine synthetaseOtherCo-authorABE, Syuhei;OIKAWA, Tadao;YAMANAKA,Kazuya2017/9/7～2017/9/8

Academic presentationFunctional analysis of the condensation domains in poly-L-lysine synthetaseOtherCo-authorABE, Syuhei;YOSHIMURA, Tomohiro;OIKAWA, Tadao;YAMANAKA, Kazuya2017/3/18～

Academic presentationImproved gene cluster direct cloning system that facilitates biosynthetic study of natural productsOtherCo-authorYASUDA, Mao;OIKAWA, Tadao;YAMANAKA, Kazuya2017/3/18～

PapersIn refereedAcademic JournalInternational coauthorship2016/11～10.1002/ange.201508576

Academic presentationOtherCo-authorTomohiro Yoshimura;Nobuyuki shibata;Yoshimitsu Hamano;Kazuya Yamanaka2015/10～

Academic presentationOtherCo-authorTomohiro Yoshimura;Nobuyuki Shibata;Yoshimitsu Hamano;Kazuya Yamanaka2015/10～

International academic conferenceOtherCo-author2015/1/11～2015/1/14

PapersIn refereedAcademic JournalInternational coauthorship2015～

PapersIn refereedAcademic JournalCo-author2015～

LectureOtherSingle-Author2014/6～

PapersIn refereedAcademic JournalInternational coauthorship2014～

PapersIn refereedAcademic JournalCo-author2014～

PapersIn refereedAcademic JournalCo-author2013～

PapersIn refereedAcademic JournalInternational coauthorship2013～

International academic conferenceOtherCo-author2012/9～

PapersIn refereedAcademic JournalInternational coauthorship2012～

International academic conferenceOtherCo-author2011/12～

International academic conferenceOtherCo-author2011/8～

PapersIn refereedAcademic JournalCo-author2011～

Academic presentationOtherCo-author2010/10～

Academic presentationOtherCo-author2010/9～

International academic conferenceOtherCo-author2010/6～

Academic presentationOtherCo-author2010/3～

PapersIn refereedAcademic JournalCo-author2010～

Academic presentationOtherCo-author2009/9～

BookIn-house publicationCo-authored chapterYAMANAKA,Kazuya2009/9～

PapersIn refereedAcademic JournalCo-authoredHAMANO, Yoshimitsu;YAMANAKA, Kazuya;MARUYAMA, Chitose;TAKAGI, Hiroshi2009/9～

International academic conferenceOtherCo-author2009/8～

Academic presentationOtherCo-author2009/7～

BookOtherCo-authored chapter2009/6～

Academic presentationOtherCo-author2009/3～

Edited bookAcademic JournalCo-author2009～

Academic presentationOtherCo-author2008/10～

Academic presentationOtherCo-author2008/8～

Academic presentationOtherCo-author2008/7～

International academic conferenceOtherCo-author2008/6～

Academic presentationOtherCo-author2008/3～

PapersIn refereedAcademic JournalCo-author2008～

Academic presentationOtherCo-author2007/9～

PapersIn refereedAcademic JournalCo-author2002～

Academic presentationOtherCo-author2001/3～

PapersIn refereedAcademic JournalCo-author2001～

Academic presentationOtherCo-author2000/10～

Academic presentationOtherCo-author2000/3～

Academic presentationOtherCo-author1999/10～

Academic presentationOtherCo-authorYAMANAKA,Kazuya1999/3～

Research Activities Overseas

Study abroadJul. 2010-Jun. 0,

Participation in International Conferences

Jun.2014
Sep.2012
Dec.2011
Aug.2011
Jun.2011
Aug.2009
Jun.2008

Courses Taught

Orientation Seminar
Biochemistry III
Fundamental Experiments of Life Science
Experiments of Life Science
Bio-Instrumental Analysis
Exercises in Thesis Projects I and II
Thesis Projects I
Thesis Projects II
Life Science Colloquium
Science and Technology English II
SeminarI（Biotechnology)
SeminarII（Biotechnology)
SeminarIII（Biotechnology)
SeminarIV（Biotechnology)
Advanced Microbial Resource Science
Advanced Microbial Resource Science